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Thread: Study: HPV vaccine prevents genital warts in males

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    OhEmGee Study: HPV vaccine prevents genital warts in males Fresh2defsheis's Avatar
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    Default Study: HPV vaccine prevents genital warts in males

    ATLANTA For the first time, an expensive vaccine aimed at preventing cervical cancer in women has proven successful at preventing a disease in men, according to a new study.

    The disease? It's genital warts, a sexually-transmitted problem that is embarrassing and uncomfortable but not life-threatening.

    Still, the results are expected to bolster a likely bid by the vaccine's manufacturer Merck & Co. Inc. to begin marketing the vaccine to boys, experts said. Merck plans to ask the government for that approval later this year.

    "This opens the door to a wonderful opportunity to prevent illness," said Anna Giuliano, a Tampa-based researcher who worked on the Merck-funded study. She is an epidemiologist at the H. Lee Moffitt Cancer Center in Tampa.

    The results of the study were to be presented Thursday at a medical conference in Europe.

    The focus was Merck's vaccine, Gardasil, which is given in three doses over six months and is priced at about $375.

    The vaccine targets the two types of HPV, or human papillomavirus, believed to be responsible for about 70 percent of cervical cancer cases, and two other types that cause most genital warts. HPV is spread through sex.

    In 2006, the U.S. government licensed the vaccine for use in girls and women ages 9 to 26. Males can spread the virus, but it was not licensed for them because there was no evidence it prevented disease in men.

    Though about 40 other countries have approved the vaccine for males, there still is no medical proof Gardasil prevents penile cancer or other HPV-associated cancers in men. There also is no evidence the vaccine prevents the spread of HPV from men to women.

    The new Merck study involved about 4,000 males ages 16 to 26. The study was done in nearly 20 countries, and included more than 1,000 males in the United States.

    It showed the vaccine was 90 percent effective in preventing genital warts, with only 15 cases of persistent infection in a vaccinated group of males as compared to 101 cases in a group that was given a fake vaccine.

    The results are "very exciting," but it's not clear they will be enough to persuade many American families to get their teenage boys vaccinated, said Dr. Maura Gillison, an HPV researcher at Johns Hopkins University who was not involved in the Merck study.

    She noted that only 1 in 4 girls have gotten the vaccine so far, despite compelling medical studies that indicate the shots prevent female cancers.

    "When parents are sitting in a room discussing with a pediatrician whether to vaccinate their child against anything, they'd like to know what the potential benefit is. A parent might say 'I'm not inclined to vaccinate my child to prevent a benign genital wart,'" she said.

    Government officials have been awaiting this interim analysis from Merck, and are eager to see additional information that may come later on the vaccine's effect on precancerous lesions, said Dr. Lauri Markowitz, an HPV expert at the U.S. Centers for Disease Control and Prevention.

    "It's obviously encouraging data but the policy makers will be looking at variety of different issues," including how cost effective the shot would be if used in males, said Markowitz, a medical epidemiologist.

    HPV causes at least 20,000 cases of cancer each year, with about a quarter of them occurring in men, according to CDC estimates. Cervical cancer is the most common type, but HPV-associated cancers of the vulva, vagina, anus, penis and head and neck also occur.

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  2. #2
    Shut Up and Drink! Study: HPV vaccine prevents genital warts in males Top shelf's Avatar
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    Default Re: Study: HPV vaccine prevents genital warts in males

    Good read!

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